Cardiovascular diseases genetics epidemiology and prevention oxford monographs on medical genetics nora james j berg kare nora audrey hart on amazoncom free shipping on qualifying offers cardiovascular diseases genetics epidemiology and prevention oxford monographs on medical genetics. The perception of genetic diseases of the heart and vascular system has dramatically changed over the last 10 years next generation sequencing and arrays with millions of single nucleotide polymorphisms allowed significant advances in the understanding of monogenic and polygenic diseases the chapters in genetics of cardiovascular diseases written by outstanding experts in the field . Note citations are based on reference standards however formatting rules can vary widely between applications and fields of interest or study the specific requirements or preferences of your reviewing publisher classroom teacher institution or organization should be applied. Cardiovascular disease cvd which represents a major health problem around the world and involves the heart brain and peripheral circulation is a complex genetic trait with multiple genetic and environmental components contributing to the observed phenotype. Introduction the pathology of and the genetic architecture of coronary heart disease coronary heart disease chd has both genetic and environmental precipitants and is a leading cause of morbidity and mortality globally 1 the major risk factors for the development of chd are male gender increasing age elevated levels of plasma low density
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