Damage to insulin producing cells in your pancreas from chronic pancreatitis can lead to diabetes a disease that affects the way your body uses blood sugar malnutrition both acute and chronic pancreatitis can cause your pancreas to produce fewer of the enzymes that are needed to break down and process nutrients from the food you eat. History facts about pancreatic enzymes pancreatic enzymes have been used since the 1800s medicinally in the treatment of exocrine pancreatic insufficiency and other digestive disorders today the world health organization considers pancreatic enzymes to be safe and essential medicines for preventing malnutrition in certain patients. Methods this review performed through a non systematic search of the available literature will provide an overview of the current knowledge of digestive enzyme supplementation in gastrointestinal disorders discussion of the use of pancreatic enzymes lactase galactosidase and conjugated bile acids and also exploring the future perspective of digestive enzyme supplementation. Exocrine pancreatic insufficiency epi causes problems in how you digest food your pancreas doesnt make enough of the enzymes that your body needs to break down and absorb nutrients enzymes . Exocrine pancreatic insufficiency epi is a malabsorptive condition that occurs when the pancreas fails to produce important digestive enzymes without these enzymes the body cannot properly digest food and absorb nutrients particularly fat
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